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Proteomics reveals dynamic metabolic changes in human hematopoietic stem progenitor cells from fetal to adulthood

15 Sept 2024

Abstract excerpt

BACKGROUND: Hematopoietic stem progenitor cells (HSPCs) undergo phenotypical and functional changes during their emergence and development. Although the molecular programs governing the development of human hematopoietic stem cells (HSCs) have been investigated broadly, the relationships between dynamic metabolic alterations and their functions remain poorly characterized. METHODS: In this study, we...

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PMID: 39278906
DOI: 10.1186/s13287-024-03930-x

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