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Article

A comparison of tools for the simulation of genomic next-generation sequencing data.

Nature reviews. Genetics - 1 Aug 2016

Escalona Merly, Rocha Sara, Posada David

Abstract excerpt

Computer simulation of genomic data has become increasingly popular for assessing and validating biological models or for gaining an understanding of specific data sets. Several computational tools for the simulation of next-generation sequencing (NGS) data have been developed in recent years, which could be used to compare existing and new NGS analytical pipelines. Here we review 23 of these tools, highlighting...

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Identifiers

PMID: 27320129
DOI: 10.1038/nrg.2016.57
PMCID: PMC5224698

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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