Article

GENOMICON-Seq: A comprehensive tool for the simulation of mutations in amplicon and whole exome sequencing

2024-08-17

Abstract excerpt

GENOMICON-Seq is a comprehensive genomic sequencing simulation tool that enables the assessment of laboratory and bioinformatics parameters influencing the detection of mutations. The tool generates genomes with mutations, mimicking processes such as low-frequency mutations, APOBEC3 activity in viruses, somatic mutations and single base substitution (SBS) mutational signals. GENOMICON-Seq adds amplicon and whole e...

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Literature Corpus work: 95b9c035-2724-57f1-abd1-930ce327d3e1
DOI: 10.1101/2024.08.14.607907

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