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Article

IntSIM: An Integrated Simulator of Next-Generation Sequencing Data.

IEEE transactions on bio-medical engineering - 1 Feb 2017

Yuan Xiguo, Zhang Junying, Yang Liying

Abstract excerpt

OBJECTIVE: Next-generation sequencing data has been widely used for DNA variant discovery and tumor study through computational tools. Effective simulation of such data with many realistic features is very necessary for testing existing tools and guiding the development of new tools. METHODS: We present an integrated simulation system, IntSIM, to simulate common DNA variants and to generate sequencing reads for...

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Identifiers

PMID: 27164567
DOI: 10.1109/TBME.2016.2560939

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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