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Article

Aggregation of FET Proteins as a Pathological Change in Amyotrophic Lateral Sclerosis.

Advances in experimental medicine and biology - 1 Jan 2017

Furukawa Yoshiaki, Tokuda Eiichi

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron disease that is characterized by the formation of abnormal inclusions in neurons. While the pathomechanism of ALS remains obscure, a number of proteins have been identified in the inclusion bodies, and the pathological roles of RNA-binding proteins have been increasingly emphasized. Among those, the FET proteins (FUS, EWSR1, TAF15) were recently...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27311318
DOI: 10.1007/5584_2016_32

Genes

EWSR1
FUS
TAF15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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