Article
RNA-Binding Proteins in Amyotrophic Lateral Sclerosis.
Molecules and cells - 30 Sept 2018
Zhao Melody, Kim Jihye Rachel, van Bruggen Rebekah, Park Jeehye
Abstract excerpt
Significant research efforts are ongoing to elucidate the complex molecular mechanisms underlying amyotrophic lateral sclerosis (ALS), which may in turn pinpoint potential therapeutic targets for treatment. The ALS research field has evolved with recent discoveries of numerous genetic mutations in ALS patients, many of which are in genes encoding RNA binding proteins (RBPs), including TDP-43, FUS, ATXN2, TAF15,...
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