Article
Amyotrophic Lateral Sclerosis, FUS and Protein Synthesis Defects.
Stem cell reviews and reports - 1 Apr 2023
Assoni Amanda Faria, Foijer Floris, Zatz Mayana
Abstract excerpt
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that mainly affects the motor system. It is a very heterogeneous disorder, so far more than 40 genes have been described as responsible for ALS. The cause of motor neuron degeneration is not yet fully understood, but there is consensus in the literature that it is the result of a complex interplay of several pathogenic processes, which include...
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