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Article

Frontotemporal lobar degeneration and amyotrophic lateral sclerosis: molecular similarities and differences.

Revue neurologique - 1 Oct 2013

Neumann M

Abstract excerpt

In the last years, new disease proteins and genes have been identified in frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS), leading to a dramatic shift in our understanding of the molecular mechanisms underlying both conditions. The vast majority of FTLD and ALS are characterized by the abnormal accumulation of TDP-43, including genetic forms associated with mutations in the genes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to RNA-Binding Protein EWS

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Source

Identifiers

PMID: 24011641
DOI: 10.1016/j.neurol.2013.07.019

Genes

FUS
GRN
TAF15
TARDBP
VCP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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