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Article

Effects of leptin and leptin receptor SNPs on clinical- and metabolic-related traits in apparent treatment-resistant hypertension.

Blood pressure - 1 Apr 2017

de Faria Ana Paula, Ritter Alessandra M V, Sabbatini Andréa R, Modolo Rodrigo, Moreno Heitor

Abstract excerpt

Leptin is associated to the lack of blood pressure control as well as target organ damage in resistant hypertensive (RH) subjects. Single-nucleotide polymorphisms (SNPs) rs7799039 and rs1137101 in leptin (LEP) and leptin receptor (LEPR) genes, respectively, are associated with cardiovascular disease and metabolic syndrome. We evaluated the association of these two SNPs with clinical and biochemical features in...

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Source

Identifiers

PMID: 27310420
DOI: 10.1080/08037051.2016.1192945

Genes

LEP
LEPR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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