Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of two well-defined polymorphisms in leptin and leptin receptor genes with hypertension and circulating leptin: a meta-analysis.

Archives of medical research - 1 Jan 2015

Li Ying-Xue, Zhang Qi, Shang Xiao-Ming, Li Yong-Qiu, Liu Xiao-Kun, Liu Chang-Qing, Liu Xiao-Ming, Zhang Qing-Hua

Abstract excerpt

BACKGROUND AND AIMS: The genes encoding adipose-derived hormone leptin and its receptor (LEPR) are increasingly deemed as hypertension-susceptibility genes. In this meta-analysis, we summarized the association of the II/I polymorphism in leptin gene and Gln223Arg polymorphism in LEPR gene with hypertension and circulating leptin. METHODS: PubMed and Embase were systematically searched. Data extraction and study...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to Essential Hypertension

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hypertension

Share to Leptin

Share to Obesity

Share to Odds Ratio

Share to Receptors, Leptin

Share to White People

Source

Identifiers

PMID: 25475696
DOI: 10.1016/j.arcmed.2014.11.012

Genes

LEPR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of two well-defined polymorphisms in leptin and leptin receptor genes with hypertension and circulating leptin: a meta-analysis.PMID 25475696Read ↗

Association of leptin receptor gene polymorphisms and essential hypertension in a Chinese population.Semantic proximity Read ↗

Association of genetic variants in Leptin, leptin receptor and adiponectin with hypertension risk and circulating Leptin/Adiponectin changes.Semantic proximity Read ↗

[Association of leptin receptor gene polymorphisms with hypertension in Chinese population: a meta-analysis].Semantic proximity Read ↗

Leptin gene polymorphism is associated with hypertension independent of obesity.Semantic proximity Read ↗

Evaluation of leptin and leptin receptor gene 3' UTR polymorphisms in essential hypertension.Semantic proximity Read ↗

-2548G>A LEP Polymorphism Is Positively Associated with Increased Leptin and Glucose Levels in Obese Saudi Patients Irrespective of Blood Pressure StatusSemantic proximity Read ↗

The association between leptin receptor gene polymorphisms and type 2 diabetes mellitus: A systematic review and meta-analysis.Semantic proximity Read ↗

Role of leptin receptor gene polymorphisms in susceptibility to the development of essential hypertension: a case-control association study in a Northern Han Chinese population.Semantic proximity Read ↗

Variations in the Obesity Gene "LEPR" Contribute to Risk of Type 2 Diabetes Mellitus: Evidence from a Meta-Analysis.Semantic proximity Read ↗

Polymorphisms in the 3'UTR of the human leptin gene and their role in hypertension.Semantic proximity Read ↗

[Association of Gln223Arg variant in leptin receptor gene with metabolic abnormalities and hypertension in type II diabetes mellitus in Shanghai "Han" population].Semantic proximity Read ↗

The -2548G/A LEP polymorphism is associated with blood pressure in Tunisian obese patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.