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Article

Adiponectin -11377C/G and +276G/T polymorphisms affect adiponectin levels but do not modify responsiveness to therapy in resistant hypertension.

Basic & clinical pharmacology & toxicology - 1 Jul 2015

de Faria Ana Paula C, Modolo Rodrigo, Sabbatini Andréa R, Barbaro Natália R, Corrêa Nathália B, Brunelli Veridiana, Tanus-Santos José E, Fontana Vanessa, Moreno Heitor

Abstract excerpt

Resistant hypertension (RHTN) is a multifactorial and polygenic disease, frequently associated with obesity. Low plasma adiponectin levels, a hormone produced by the adipose tissue, were associated with RHTN. Single nucleotide polymorphisms (SNPs) -11377C/G (rs266729) and +276G/T (rs1501299) in ADIPOQ (adiponectin gene) were associated with hypertension. This study evaluated the association between two SNPs...

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Identifiers

PMID: 25546819
DOI: 10.1111/bcpt.12368

Genes

ADIPOQ

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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