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Article

Identification of a region in the coiled-coil domain of Smc3 that is essential for cohesin activity.

Nucleic acids research - 27 Jul 2016

Orgil Ola, Mor Hadar, Matityahu Avi, Onn Itay

Abstract excerpt

The cohesin complex plays an important role in sister chromatin cohesion. Cohesin's core is composed of two structural maintenance of chromosome (SMC) proteins, called Smc1 and Smc3. SMC proteins are built from a globular hinge domain, a rod-shaped domain composed of long anti-parallel coiled-coil (CC), and a second globular adenosine triphosphatase domain called the head. The functions of both head and hinge...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27307603
DOI: 10.1093/nar/gkw539
PMCID: PMC5291275

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Identification of a region in the coiled-coil domain of Smc3 that is essential for cohesin activity.PMID 27307603Read ↗

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