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Article

Specificity of the connexin W3/4 locus for functional gap junction formation.

Channels (Austin, Tex.) - 1 Nov 2016

Xu Qin, Lin Xianming, Matiukas Arvydas, Zhang Xian, Veenstra Richard D

Abstract excerpt

The N-terminal (NT) domain of the connexins forms an essential transjunctional voltage (Vj) sensor and pore-forming domain that when truncated, tagged, or mutated often leads to formation of a nonfunctional channel. The NT domain is relatively conserved among the connexins though the α- and δ-group connexins possess a G2 residue not found in the β- and γ-group connexins. Deletion of the connexin40 G2 residue...

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Source

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Identifiers

PMID: 27304225
DOI: 10.1080/19336950.2016.1200775
PMCID: PMC5034775

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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