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HOXC10 Expression Supports the Development of Chemotherapy Resistance by Fine Tuning DNA Repair in Breast Cancer Cells

15 Jun 2016

Abstract excerpt

Development of drug resistance is a major factor limiting the continued success of cancer chemotherapy. To overcome drug resistance, understanding the underlying mechanism(s) is essential. We found that HOXC10 is overexpressed in primary carcinomas of the breast, and even more significantly in distant metastasis arising after failed chemotherapy. High HOXC10 expression correlates with shorter recurrence-free and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 27302171
DOI: 10.1158/0008-5472.can-16-0774

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