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Article

Delineating genetic alterations for tumor progression in the MCF10A series of breast cancer cell lines.

PloS one - 15 Feb 2010

Kadota Mitsutaka, Yang Howard H, Gomez Bianca, Sato Misako, Clifford Robert J, Meerzaman Daoud, Dunn Barbara K, Wakefield Lalage M, Lee Maxwell P

Abstract excerpt

To gain insight into the role of genomic alterations in breast cancer progression, we conducted a comprehensive genetic characterization of a series of four cell lines derived from MCF10A. MCF10A is an immortalized mammary epithelial cell line (MEC); MCF10AT is a premalignant cell line generated...

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Identifiers

PMID: 20169162
DOI: 10.1371/journal.pone.0009201
PMCID: PMC2821407

Genes

RUNX1
HRAS
MYC
AKT1
CDH13
FHIT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20169162-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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