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Article

Identification and characterization of small RNAs in Yersinia pestis.

RNA biology - 1 Mar 2013

Beauregard Arthur, Smith Eric A, Petrone Brianna L, Singh Navjot, Karch Christopher, McDonough Kathleen A, Wade Joseph T

Abstract excerpt

Yersinia pestis, the etiologic agent of plague, is closely related to Yersinia pseudotuberculosis evolutionarily but has a very different mode of infection. The RNA-binding regulatory protein, Hfq, mediates regulation by small RNAs (sRNAs) and is required for virulence of both Y. pestis and Y. pseudotuberculosis. Moreover, Hfq is required for growth of Y. pestis, but not Y. pseudotuberculosis, at 37°C. Together,...

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Identifiers

PMID: 23324607
DOI: 10.4161/rna.23590
PMCID: PMC3672283

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