Article
Control of Clostridium difficile Physiopathology in Response to Cysteine Availability
14 Jun 2016
Abstract excerpt
The pathogenicity of Clostridium difficile is linked to its ability to produce two toxins: TcdA and TcdB. The level of toxin synthesis is influenced by environmental signals, such as phosphotransferase system (PTS) sugars, biotin, and amino acids, especially cysteine. To understand the molecular mechanisms of cysteine-dependent repression of toxin production, we reconstructed the sulfur metabolism pathways of C....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
