Article
Regulation of Cysteine Homeostasis and Its Effect on Escherichia coli Sensitivity to Ciprofloxacin in LB Medium.
International journal of molecular sciences - 17 Apr 2024
Smirnova Galina, Tyulenev Aleksey, Sutormina Lyubov, Kalashnikova Tatyana, Muzyka Nadezda, Ushakov Vadim, Samoilova Zoya, Oktyabrsky Oleg
Abstract excerpt
Cysteine and its derivatives, including H2S, can influence bacterial virulence and sensitivity to antibiotics. In minimal sulfate media, H2S is generated under stress to prevent excess cysteine and, together with incorporation into glutathione and export into the medium, is a mechanism of cysteine homeostasis. Here, we studied the features of cysteine homeostasis in LB medium, where the main source of sulfur is...
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