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Article

Factors supporting cysteine tolerance and sulfite production in Candida albicans.

Eukaryotic cell - 1 Apr 2013

Hennicke Florian, Grumbt Maria, Lermann Ulrich, Ueberschaar Nico, Palige Katja, Böttcher Bettina, Jacobsen Ilse D, Staib Claudia, Morschhäuser Joachim, Monod Michel, Hube Bernhard, Hertweck Christian, Staib Peter

Abstract excerpt

The amino acid cysteine has long been known to be toxic at elevated levels for bacteria, fungi, and humans. However, mechanisms of cysteine tolerance in microbes remain largely obscure. Here we show that the human pathogenic yeast Candida albicans excretes sulfite when confronted with increasing cysteine concentrations. Mutant construction and phenotypic analysis revealed that sulfite formation from cysteine in...

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Identifiers

PMID: 23417561
DOI: 10.1128/EC.00336-12
PMCID: PMC3623443

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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