Article
Methionine overaccumulation reinforces heterochromatic non-CG hypermethylation and transposon silencing in Arabidopsis.
Plant physiology - 4 Aug 2026
Yerushalmy Yonatan, Lieberman-Lazarovich Michal, Mohanty Devasantosh, Mittler Ron, Amir Rachel, Hacham Yael
Abstract excerpt
Methionine is a key sulfur-containing amino acid and the precursor of S-adenosylmethionine, the universal methyl donor for DNA and histone methylation. While reduced S-adenosylmethionine availability is known to cause DNA hypomethylation, the effects of elevated methionine/S-adenosylmethionine remain poorly understood. Here, we addressed the effect of elevated methionine using the mto1 mutant of Arabidopsis...
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