Methylenetetrahydrofolate reductase modulates methyl metabolism and lignin monomer methylation in maize.

doi:10.1093/jxb/ery208

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Article

Methylenetetrahydrofolate reductase modulates methyl metabolism and lignin monomer methylation in maize.

Journal of experimental botany - 18 Jul 2018

Wu Zhenying, Ren Hao, Xiong Wangdan, Roje Sanja, Liu Yuchen, Su Kunlong, Fu Chunxiang

Abstract excerpt

The brown midrib2 (bm2) mutant of maize, which has a modified lignin composition, contains a mutation in the methylenetetrahydrofolate reductase (MTHFR) gene. Here, we show that a MITE transposon insertion caused down-regulation of MTHFR, with an accompanying decrease in 5-methyl-tetrahydrofolate and an increase in 5, 10-methylene-tetrahydrofolate and tetrahydrofolate in the bm2 mutant. Furthermore, MTHFR...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29860438
DOI: 10.1093/jxb/ery208

Genes

MTHFR
COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.