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The Potential Role of PTPN-22 C1858T Gene Polymorphism in the Pathogenesis of Type 1 Diabetes in Saudi Population.

Immunological investigations - 1 Jul 2018

Alswat Khaled A, Nasr Amre, Al Dubayee Mohammed S, Talaat Iman M, Alsulaimani Adnan A, Mohamed Imad A A, Allam Gamal

Abstract excerpt

BACKGROUND: Recent investigations have reported an association between protein tyrosine phosphatase non-receptor type-22 (PTPN-22) gene polymorphism and susceptibility to the development of type 1 diabetes (T1D) in some populations and not in others. In this study, we aimed to investigate the association of PTPN-22 C1858T polymorphism with T1D in Saudi children. METHODS: A cohort of 372 type 1 diabetic children...

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Biomarkers
C-Peptide
Diabetes Mellitus, Type 1
Glycated Hemoglobin
Logistic Models

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Protein Tyrosine Phosphatase, Non-Receptor Type 22

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PMID: 29611765
DOI: 10.1080/08820139.2018.1458109

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