Article
The association between PTPN22 C1858T gene polymorphism and type 1 diabetes mellitus: an Indonesian study.
Annals of medicine - 1 Dec 2023
Rochmah Nur, Arief Fatimah, Faizi Muhammad, Basuki Sukmawati
Abstract excerpt
BACKGROUND: Type 1 diabetes mellitus (T1DM) is disease caused by the destruction of β pancreatic cells. The activation of T-lymphocyte and proliferation inhibitor are induced by protein tyrosine phosphatase non-receptor type 22 (PTPN22). However, the link between PTPN22 C1858T gene polymorphism and T1DM is still controversy. This study aimed to analyse the C1858T gene polymorphism in Indonesian children with...
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