Article
Systems proteomics of liver mitochondria function.
Science (New York, N.Y.) - 10 Jun 2016
Williams Evan G, Wu Yibo, Jha Pooja, Dubuis Sébastien, Blattmann Peter, Argmann Carmen A, Houten Sander M, Amariuta Tiffany, Wolski Witold, Zamboni Nicola, Aebersold Ruedi, Auwerx Johan
Abstract excerpt
Recent improvements in quantitative proteomics approaches, including Sequential Window Acquisition of all Theoretical Mass Spectra (SWATH-MS), permit reproducible large-scale protein measurements across diverse cohorts. Together with genomics, transcriptomics, and other technologies, transomic data sets can be generated that permit detailed analyses across broad molecular interaction networks. Here, we examine...
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