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Article

Ecological factors drive natural selection pressure of avian aryl hydrocarbon receptor 1 genotypes.

Scientific reports - 10 Jun 2016

Hwang Ji-Hee, Park Jin-Young, Park Hae-Jeong, Bak Su-Min, Hirano Masashi, Iwata Hisato, Park Young-Suk, Kim Eun-Young

Abstract excerpt

The aryl hydrocarbon receptor (AHR) mediates dioxin toxicities. Several studies have suggested that two amino acid residues corresponding to the 324(th) and 380(th) positions in the ligand binding domain (LBD) of the chicken AHR1 (Ile_Ser as high sensitivity, Ile_Ala as moderate sensitivity, and Val_Ala as low sensitivity), could be an important factor determining dioxin sensitivity in avian species. Here, we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27283192
DOI: 10.1038/srep27526
PMCID: PMC4901312

Genes

AHR

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