Article
Amino acid sequence of the AhR1 ligand-binding domain predicts avian sensitivity to dioxin like compounds: in vivo verification in European starlings.
Environmental toxicology and chemistry - 1 Dec 2014
Eng Margaret L, Elliott John E, Jones Stephanie P, Williams Tony D, Drouillard Ken G, Kennedy Sean W
Abstract excerpt
Research has demonstrated that the sensitivity of avian species to the embyrotoxic effects of dioxin-like compounds can be predicted by the amino acid identities at two key sites within the ligand-binding domain of the aryl hydrocarbon receptor 1 (AhR1). The domestic chicken (Gallus gallus domesticus) has been established as a highly sensitive species to the toxic effects of dioxin-like compounds. Results from...
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