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Article

Key amino acids in the aryl hydrocarbon receptor predict dioxin sensitivity in avian species.

Environmental science & technology - 1 Oct 2008

Head Jessica A, Hahn Mark E, Kennedy Sean W

Abstract excerpt

Dioxin-like compounds are toxic to most vertebrates, but significant differences in sensitivity exist among species. A recent study suggests that the amino acid residues corresponding to Ile324 and Ser380 in the chicken aryl hydrocarbon receptor 1 (AHR1) are important determinants of differential biochemical responses to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in chickens and common terns. Here, we investigate...

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PMID: 18939598
DOI: 10.1021/es801082a

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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