Article
A simple strategy guides the complex metabolic regulation in Escherichia coli.
Scientific reports - 10 Jun 2016
Facchetti Giuseppe
Abstract excerpt
A way to decipher the complexity of the cellular metabolism is to study the effect of different external perturbations. Through an analysis over a sufficiently large set of gene knockouts and growing conditions, one aims to find a unifying principle that governs the metabolic regulation. For instance, it is known that the cessation of the microorganism proliferation after a gene deletion is only transient....
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