Article
TNF-alpha, TNF-beta, IL-6, and IL-10 polymorphisms in patients with lung cancer.
Disease markers - 1 Jan 2005
Seifart Carola, Plagens Alexandra, Dempfle Astrid, Clostermann Ursula, Vogelmeier Claus, von Wichert Peter, Seifart Ulf
Abstract excerpt
Apart from cigarette smoking, genetic factors seem to be of importance in the development of lung cancer. The present case-control study investigated frequencies of five inflammatory response gene polymorphisms (TNF-alpha-308, TNF-beta-Intron1-252, IL-6-174, IL-10-819 and IL-10-1082) in patients with lung cancer and controls. The study population consisted of 117 patients with lung cancer (77 patients with NSCLC,...
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