Article
Interleukin-10 (IL-10) promoter genotypes are associated with lung cancer risk in Taiwan males and smokers.
Anticancer research - 1 Dec 2014
Hsia Te-Chun, Chang Wen-Shin, Liang Shinn-Jye, Chen Wei-Chun, Tu Chih-Yen, Chen Hung-Jen, Yang Mei-Due, Tsai Chia-Wen, Hsu Chin-Mu, Tsai Chang-Hai, Bau Da-Tian
Abstract excerpt
Interleukin-10 (IL-10) is an immunosuppressive cytokine involved in carcinogenesis via immune escape. The present study aimed at evaluating the contribution of IL-10 promoter A-1082G (rs1800896), T-819C (rs3021097), A-592C (rs1800872) genetic polymorphisms to the risk of lung cancer in Taiwan. Associations of three IL-10 polymorphic genotypes with lung cancer risk were investigated among 358 lung cancer patients...
Topics
- Female
- Gene Frequency
- Genetic Association Studies
