Article
Interleukin-18 promoter polymorphism is associated with lung cancer: a case-control study.
Acta oncologica (Stockholm, Sweden) - 1 Jan 2009
Farjadfar Akbar, Mojtahedi Zahra, Ghayumi Mohammad Ali, Erfani Nasrollah, Haghshenas Mohammad Reza, Ghaderi Abbas
Abstract excerpt
BACKGROUND: Interleukin-18 (IL-18) is a multifunctional cytokine that augments IFN-gamma production and affects tumor immune response. In the present case-control study, we tested whether IL-18 promoter polymorphism contributes to lung cancer susceptibility in Iranian patients. MATERIAL AND METHODS: The study groups were 73 patients with lung cancer, including 53 with squamous carcinoma (SC) and 20 with small...
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