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Article

Deep sequencing increases hepatitis C virus phylogenetic cluster detection compared to Sanger sequencing.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Sept 2016

Montoya Vincent, Olmstead Andrea, Tang Patrick, Cook Darrel, Janjua Naveed, Grebely Jason, Jacka Brendan, Poon Art F Y, Krajden Mel

Abstract excerpt

Effective surveillance and treatment strategies are required to control the hepatitis C virus (HCV) epidemic. Phylogenetic analyses are powerful tools for reconstructing the evolutionary history of viral outbreaks and identifying transmission clusters. These studies often rely on Sanger sequencing which typically generates a single consensus sequence for each infected individual. For rapidly mutating viruses such...

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PMID: 27282472
DOI: 10.1016/j.meegid.2016.06.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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