Article
The Influence of Hepatitis C Virus Genetic Region on Phylogenetic Clustering Analysis.
PloS one - 1 Jan 2015
Lamoury François M J, Jacka Brendan, Bartlett Sofia, Bull Rowena A, Wong Arthur, Amin Janaki, Schinkel Janke, Poon Art F, Matthews Gail V, Grebely Jason, Dore Gregory J, Applegate Tanya L
Abstract excerpt
Sequencing is important for understanding the molecular epidemiology and viral evolution of hepatitis C virus (HCV) infection. To date, there is little standardisation among sequencing protocols, in-part due to the high genetic diversity that is observed within HCV. This study aimed to develop a novel, practical sequencing protocol that covered both conserved and variable regions of the viral genome and assess...
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