Article
Air pollution and diabetes association: Modification by type 2 diabetes genetic risk score.
Environment international - 1 Sept 2016
Eze Ikenna C, Imboden Medea, Kumar Ashish, von Eckardstein Arnold, Stolz Daiana, Gerbase Margaret W, Künzli Nino, Pons Marco, Kronenberg Florian, Schindler Christian, Probst-Hensch Nicole
Abstract excerpt
Exposure to ambient air pollution (AP) exposure has been linked to type 2 diabetes (T2D) risk. Evidence on the impact of T2D genetic variants on AP susceptibility is lacking. Compared to single variants, joint genetic variants contribute substantially to disease risk. We investigated the modification of AP and diabetes association by a genetic risk score (GRS) covering 63 T2D genes in 1524 first follow-up...
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