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Association between combined exposure to ambient air pollutants, genetic risk, and incident gout risk: A prospective cohort study in the UK Biobank.

Seminars in arthritis and rheumatism - 1 Jun 2024

Liu Wei, Ye Lihong, Hua Baojie, Yang Yudan, Dong Ziwei, Jiang Yuqing, Li Jiayu, Sun Xiaohui, Ye Ding, Wen Chengping, Mao Yingying, He Zhixing

Abstract excerpt

BACKGROUND: Limited research has been conducted on the association between long-term exposure to air pollutants and the incidence of gout. OBJECTIVES: This study aims to assess the individual and combined effects of prolonged exposure to five air pollutants (NO2, NOx, PM10, PMcoarse and PM2.52) on the incidence of gout among 458,884 initially gout-free participants enrolled in the UK Biobank. METHODS: Employing a...

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PMID: 38579592
DOI: 10.1016/j.semarthrit.2024.152445

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