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Ambient air pollution, lifestyle, and genetic predisposition associated with type 2 diabetes: findings from a national prospective cohort study.

The Science of the total environment - 25 Nov 2022

Li Rui, Cai Miao, Qian Zhengmin Min, Wang Xiaojie, Zhang Zilong, Wang Chongjian, Wang Yuqin, Arnold Lauren D, Howard Steven W, Li Haitao, Lin Hualiang

Abstract excerpt

BACKGROUND: The combined effects of ambient air pollution, lifestyle, and genetic predisposition on incident Type 2 Diabetes (T2D) have not been well documented. METHODS: A total of 263,733 participants without T2D at baseline were identified from the UK Biobank. Annual concentrations of five air pollutants were estimated using Land Use Regression, while a healthy lifestyle score (HLS) was constructed using 7...

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PMID: 35934032
DOI: 10.1016/j.scitotenv.2022.157838

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