Article
Derivation of hybrid ES cell lines from two different strains of mice.
Stem cell research - 1 Mar 2016
Lau Ho-Tak, Liu Lizhi, Ray Chelsea, Bell Fong T, Li Xiajun
Abstract excerpt
Parental origin-dependent expression of the imprinted genes is essential for mammalian development. Zfp57 maintains genomic imprinting in mouse embryos and ES cells. To examine the allelic expression patterns of the imprinted genes in ES cells, we obtained multiple hybrid ES clones that were directly derived from the blastocysts generated from the cross between mice on two different genetic backgrounds. The...
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