Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Disruption of imprinting and aberrant embryo development in completely inbred embryonic stem cell-derived mice.

Development, growth & differentiation - 1 Sept 2007

Deng Tao, Kuang Ying, Zhang Dan, Wang Long, Sun Ruilin, Xu Guojiang, Wang Zhugang, Fei Jian

Abstract excerpt

The completely embryonic stem (ES) cell-derived mice (ES mice) produced by tetraploid embryo complementation provide us with a rapid and powerful approach for functional genome analysis. However, inbred ES cell lines often fail to generate ES mice. The genome of mouse ES cells is extremely unstable during in vitro culture and passage, and the expression of the imprinted genes is most likely to be affected....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to DNA Methylation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Primers

Share to Embryonic Development

Share to Embryonic Stem Cells

Share to Genomic Imprinting

Share to Mice, Inbred C57BL

Share to Mice, Inbred CBA

Source

Identifiers

PMID: 17635532
DOI: 10.1111/j.1440-169X.2007.00955.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Disruption of imprinting and aberrant embryo development in completely inbred embryonic stem cell-derived mice.PMID 17635532Read ↗

Altered imprinted gene methylation and expression in completely ES cell-derived mouse fetuses: association with aberrant phenotypes.Semantic proximity Read ↗

Disruption of imprinting in cloned mouse fetuses from embryonic stem cellsSemantic proximity Read ↗

Monoallelic expression and methylation of imprinted genes in human and mouse embryonic germ cell lineages.Semantic proximity Read ↗

Mouse parthenogenetic embryos with monoallelic H19 expression can develop to day 17.5 of gestation.Semantic proximity Read ↗

Imprinting defects in mouse embryos: stochastic errors or polymorphic phenotype?Semantic proximity Read ↗

Epigenotype switching of imprintable loci in embryonic germ cells.Semantic proximity Read ↗

Igf2-H19, an imprinted tandem gene, is an important regulator of embryonic development, a guardian of proliferation of adult pluripotent stem cells, a regulator of longevity, and a ‘passkey’ to cancerogenesisSemantic proximity Read ↗

<i>H19</i> Imprinting Control Region Methylation Requires an Imprinted Environment Only in the Male Germ LineSemantic proximity Read ↗

Modulation of imprinted gene network in placenta results in normal development of in vitro manipulated mouse embryosSemantic proximity Read ↗

IVF results in de novo DNA methylation and histone methylation at an Igf2-H19 imprinting epigenetic switchSemantic proximity Read ↗

Regulatory mechanisms at the mouse Igf2/H19 locus.Semantic proximity Read ↗

A functional analysis of imprinting in parthenogenetic embryonic stem cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.