Article
Kit receptor tyrosine kinase dysregulations in feline splenic mast cell tumours.
Veterinary and comparative oncology - 1 Sept 2017
Sabattini S, Barzon G, Giantin M, Lopparelli R M, Dacasto M, Prata D, Bettini G
Abstract excerpt
This study investigated Kit receptor dysregulations (cytoplasmic immunohistochemical expression and/or c-KIT mutations) in cats affected with splenic mast cell tumours. Twenty-two cats were included. Median survival time was 780 days (range: 1-1219). An exclusive splenic involvement was significantly (P = 0.042) associated with longer survival (807 versus 120 days). Eighteen tumours (85.7%) showed Kit cytoplasmic...
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