Article
Metabolites of the Polycyclic Aromatic Hydrocarbon Phenanthrene in the Urine of Cigarette Smokers from Five Ethnic Groups with Differing Risks for Lung Cancer.
PloS one - 1 Jan 2016
Patel Yesha M, Park Sungshim L, Carmella Steven G, Paiano Viviana, Olvera Natalie, Stram Daniel O, Haiman Christopher A, Le Marchand Loic, Hecht Stephen S
Abstract excerpt
Results from the Multiethnic Cohort Study demonstrated significant differences in lung cancer risk among cigarette smokers from five different ethnic/racial groups. For the same number of cigarettes smoked, and particularly among light smokers, African Americans and Native Hawaiians had the highest risk for lung cancer, Whites had intermediate risk, while Latinos and Japanese Americans had the lowest risk. We...
Topics
- Aged
- Female
- Gene Dosage
- Glutathione Transferase
- Humans
- Lung Neoplasms
- Male
- Middle Aged
- Mutation
- Neoplasm Proteins
- Phenanthrenes
- Risk Factors
- Smoking