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Article

Immunohistochemical Evaluation of the Role of p53 Mutation in Cervical Cancer: Ser-20 p53-Mutant Correlates with Better Prognosis.

Anticancer research - 1 Jun 2016

Freier Christoph P, Stiasny Annika, Kuhn Christina, Mayr Doris, Alexiou Christoph, Janko Christina, Wiest Irmi, Jeschke Udo, Kost Bernd

Abstract excerpt

BACKGROUND: Cervical cancer is driven by human papillomavirus virus-specific oncoprotein E6. E6 interacts with E3 ubiquitin-protein ligase, resulting in the proteolysis of p53 protein. The aim of this study was to analyze one TP53 mutation in patients with cervical cancer and to correlate it to prognosis. MATERIALS AND METHODS: A total of 248 paraffin-embedded tumor samples were stained for mutated p53 protein....

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PMID: 27272838

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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