Back to search

Article

Progressive p53 Expression in the Histological Spectrum of Cervical Neoplasia

2025-10-17

Abstract excerpt

<title>Abstract</title> <p>Background The development of cervical cancer is significantly influenced by the dysregulation of the tumor suppressor p53. While TP53 mutations are frequently present in HPV-independent malignancies, as evidenced by abnormal immunohistochemistry (IHC) patterns, E6-mediated degradation in HPV-associated illness reduces p53 function. This study examined p53 expression in a Nigerian cohor...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
b6cb6bf8-c1f1-57b1-9ecb-548d056bb11e
DOI
10.21203/rs.3.rs-7567894/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Progressive p53 Expression in the Histological Spectrum of Cervical NeoplasiaDOI 10.21203/rs.3.rs-7567894/v1
Synchronicity of P53 Mutation and Multiple High-Risk HPV Genotypes, and the Risk of Cervical Cancer among Women in Osogbo, NigeriaSemantic proximity
Immunohistochemical Evaluation of the Role of p53 Mutation in Cervical Cancer: Ser-20 p53-Mutant Correlates with Better Prognosis.Semantic proximity
Exploring the p53 connection of cervical cancer pathogenesis involving north-east Indian patients.Semantic proximity
The role of TP53 in Cervical carcinogenesis.Semantic proximity
The role of p16 as putative biomarker for cervical neoplasia: A controversial issue?Semantic proximity
Deregulation of the G1/S phase transition in cancer and squamous intraepithelial lesions of the uterine cervix: A case control studySemantic proximity
A comparative analysis of clinical and molecular factors with the stage of cervical cancer in a Brazilian cohort.Semantic proximity
Phenotypic features with p53 alterations related to human papillomavirus and prognostic evaluation in cervical cancer.Semantic proximity
Active human papillomavirus involvement in Barrett's dysplasia and oesophageal adenocarcinoma is characterized by wild‐type p53 and aberrations of the retinoblastoma protein pathwaySemantic proximity
The presence of human papillomavirus-16/-18 E6, p53, and Bcl-2 protein in cervicovaginal smears from patients with invasive cervical cancer.Semantic proximity
p53 Immunohistochemistry Defines a Subset of Human Papillomavirus-Independent Penile Squamous Cell Carcinomas with Adverse PrognosisSemantic proximity
Frequent occurrence of p53 gene mutations in uterine cancers at advanced clinical stage and with aggressive histological phenotypes.Semantic proximity
Select a neighboring publication to make it the new centre.