Article
Expression of HPV-16 E6 Protein and p53 Inactivation Increases the Uterine Cervical Cancer Invasion
15 May 2014
Abstract excerpt
INTRODUCTION: Human papillomavirus infection (HPV-16) and expression of HPV E6 protein are the major risk factors of cervical cancer. Studies reported that expression of E6 protein adversely affect the function of p53 and thus involved in tumor progression. In the present study, we made an attempt to analyze the prevalence of HPV-16 association, E6 and p53 expression in cervical cancer tissues. METHODS: Uterine...
