Article
Isolation and functional analysis of five HPVE6 variants with respect to p53 degradation.
Journal of medical virology - 1 Mar 2008
Hiller Thomas, Stubenrauch Frank, Iftner Thomas
Abstract excerpt
Persistent infection with high risk human papillomavirus is a necessary risk factor in the etiology of invasive cervical carcinoma. With regard to molecular details, the best studied types are HPV16 and HPV18 which are found in 70% of cervical cancer worldwide, however factors associated with the progression of individual cervical intraepithelial neoplasias into cancer are still poorly understood. Intratype amino...
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