Article
Thrombotic risk correlates with mutational status in true essential thrombocythemia.
European journal of clinical investigation - 1 Aug 2016
Bertozzi Irene, Peroni Edoardo, Coltro Giacomo, Bogoni Giulia, Cosi Elisabetta, Santarossa Claudia, Fabris Fabrizio, Randi Maria L
Abstract excerpt
BACKGROUND: True essential thrombocythemia (ET) may carry one of the known driver mutations (JAK2, MPL and CALR) or none of them [in triple-negative (3NEG) cases]. The patients' mutational status seems to delineate the clinical manifestations of ET. MATERIALS AND METHODS: We report the data of 183 patients diagnosed with ET strictly according to the WHO 2008 criteria and with a full molecular diagnosis, including...
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