The risk of thrombosis in essential thrombocythemia is associated with the type of CALR mutation: A multicentre collaborative study.

doi:10.1111/ejh.13561

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Article

The risk of thrombosis in essential thrombocythemia is associated with the type of CALR mutation: A multicentre collaborative study.

European journal of haematology - 1 Mar 2021

Pérez Encinas Manuel M, Sobas Marta, Gómez-Casares María Teresa, Abuin Blanco Aitor, Noya Pereira María Soledad, Raya José María, Andrade-Campos Marcio M, Álvarez Larrán Alberto, Lewandowski Krzysztof, Łukasz Szukalski, Hernández Boluda Juan Carlos, Ferrer-Marín Francisca, Fox María Laura, Gołos Aleksandra, Gasior Kabat Mercedes, Magro Mazo Elena, Czyż Anna, Martín Martín Alejandro, Bellosillo Paricio Beatriz, Quinteiro García Celsa, González Martín Jesús María, Stuckey Ruth

Abstract excerpt

OBJECTIVES: In patients with essential thrombocythemia (ET), after the JAK2V617F driver mutation, mutations in CALR are common (classified as type 1, 52-bp deletion or type 2, 5-bp insertion). CALR mutations have generally been associated with a lower risk of thrombosis. This study aimed to confirm the impact of CALR mutation type on thrombotic risk. METHODS: We retrospectively investigated 983 ET patients...

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PMID: 33275803
DOI: 10.1111/ejh.13561

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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