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Article

Single-Fiber Recordings of Nociceptive Fibers in Patients With HSAN Type V With Congenital Insensitivity to Pain.

The Clinical journal of pain - 1 Jul 2016

Sagafos Dagrun, Kleggetveit Inge P, Helås Tormod, Schmidt Roland, Minde Jan, Namer Barbara, Schmelz Martin, Jørum Ellen

Abstract excerpt

OBJECTIVES: Nerve growth factor (NGF) is a protein important for growth and survival, but also for modulation of sensitivity of nociceptors and sympathetic neurons. The purpose of the present study was to investigate the effects of reduced NGF signaling in patients with hereditary sensory and autonomic neuropathies type V, congenital insensitivity to pain, caused by a mutation of the NGFβ gene, including a...

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Source

Identifiers

PMID: 27270876
DOI: 10.1097/AJP.0000000000000303

Genes

NGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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