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Article

Recurrent Mutations in the MTOR Regulator RRAGC in Follicular Lymphoma.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Nov 2016

Ying Zhang Xiao, Jin Meiyan, Peterson Luke F, Bernard Denzil, Saiya-Cork Kamlai, Yildiz Mehmet, Wang Shaomeng, Kaminski Mark S, Chang Alfred E, Klionsky Daniel J, Malek Sami N

Abstract excerpt

PURPOSE: This study was performed to further our understanding of the biological and genetic basis of follicular lymphoma and to identify potential novel therapy targets. EXPERIMENTAL DESIGN: We analyzed previously generated whole exome sequencing data of 23 follicular lymphoma cases and one transformed follicular lymphoma case and expanded findings to a combined total of 125 follicular lymphoma/3 transformed...

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Topics

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Share to Amino Acids
Share to Genes, Tumor Suppressor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Guanosine Diphosphate

Share to Guanosine Triphosphate

Share to Lymphoma, Follicular

Share to Monomeric GTP-Binding Proteins

Share to Neoplasm Recurrence, Local

Share to TOR Serine-Threonine Kinases

Source

Open in PubMed Open full text

Identifiers

PMID: 27267853
DOI: 10.1158/1078-0432.CCR-16-0609
PMCID: PMC5093058

Genes

RRAGC
MTOR
FLCN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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