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Article

Recurrent somatic mutations affecting B-cell receptor signaling pathway genes in follicular lymphoma.

Blood - 26 Jan 2017

Krysiak Kilannin, Gomez Felicia, White Brian S, Matlock Matthew, Miller Christopher A, Trani Lee, Fronick Catrina C, Fulton Robert S, Kreisel Friederike, Cashen Amanda F, Carson Kenneth R, Berrien-Elliott Melissa M, Bartlett Nancy L, Griffith Malachi, Griffith Obi L, Fehniger Todd A

Abstract excerpt

Follicular lymphoma (FL) is the most common form of indolent non-Hodgkin lymphoma, yet it remains only partially characterized at the genomic level. To improve our understanding of the genetic underpinnings of this incurable and clinically heterogeneous disease, whole-exome sequencing was performed on tumor/normal pairs from a discovery cohort of 24 patients with FL. Using these data and mutations identified in...

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Share to Agammaglobulinaemia Tyrosine Kinase
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Lymphoma, Follicular

Share to Receptors, Antigen, B-Cell

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Source

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Identifiers

PMID: 28064239
DOI: 10.1182/blood-2016-07-729954
PMCID: PMC5270390

Genes

BCR
HVCN1
BTK
CREBBP
CXCR4
EGR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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