Article
Association of TLR9-1237T>C; rs5743836 polymorphism with increased risk of Hodgkin's lymphoma: A case-control study.
PloS one - 1 Jan 2022
Al-Khatib Sohaib, Shabaneh Amin, Abdo Nour, Al-Eitan Laith, Al-Mistarehi Abdel-Hameed, Khader Yousef
Abstract excerpt
Mature B-cell neoplasms are typically divided into Hodgkin and Non-Hodgkin Lymphomas. Hodgkin Lymphoma is characterized by the neoplastic Reed-Sternberg cells, usually harbored in an inflammatory background, with a frequent clinical presentation of mediastinal lymphadenopathy. Many studies link between autoimmunity and lymphomagenesis, a large proportion of these studies evidently trace the pathogenesis back to...
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